Human cyp11a1
Web31 mei 2010 · Crystal structure of human CYP11A1 in complex with 20,22-dihydroxycholesterol. PDB DOI: 10.2210/pdb3NA0/pdb; Classification: Oxidoreductase, … WebThe expression of CYP11A1 in the nervous system allows neurosteroids to be synthesized de novo. In the classic steroidogenic tissues, adrenals and gonads, the key regulator controlling CYP11A1 expression is steroidogenic factor-1 (SF-1), but the transcriptional regulation of CYP11A1 in the brain is unclear.
Human cyp11a1
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WebHuman Ortholog CYP11A1, cytochrome P450 family 11 subfamily A member 1 Vertebrate Orthologs 4 Human Diseases more Diseases 2 with human CYP11A1 …
Web27 jun. 2007 · The CYP11A1 gene encodes the cholesterol side-chain cleavage enzyme, also termed cytochrome P450scc, which catalyzes the conversion of cholesterol to pregnenolone in the first step of steroid biosynthesis in mitochondria. Web15 jun. 2024 · CYP11A1, a member of the cytochrome P450 family, plays several key roles in the human body. It catalyzes the first and rate-limiting step in steroidogenesis, converting cholesterol to pregnenolone. Aside from the classical steroidogenic tissues such as the adrenals, gonads and placenta, CYP11A1 has …
WebCytochrome P450 side-chain cleavage enzyme, encoded by the CYP11A1 gene, catalyzes the first and rate-limiting step of steroid hormone biosynthesis. Previous morpholino-knockdown studies in zebrafish suggested cyp11a2 is a functional equivalent of human CYP11A1 and is essential for interrenal steroi … WebThe CYP11A1 encodes cytochrome P450scc, catalyzing the first step of steroidogenesis in adrenals and gonads under the control of cAMP-mediated hormonal signals. The cAMP …
WebCYP11A1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. Assigned HPA protein class (es) for the encoded ...
WebCYP11A1 Antibodies. Antibodies that detect CYP11A1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, … napa forest ohioWeb31 mei 2010 · PubMed Abstract: In humans, the precursor to all steroid hormones, pregnenolone, is synthesized from cholesterol by an enzyme complex comprising adrenodoxin reductase (AdR), adrenodoxin (Adx), and a cytochrome P450 (P450scc or CYP11A1). This complex not only plays a key role in steroidogenesis, but also has long … napa forsyth mtWeb细胞色素P45011A1抗体公司正在出售的产品：海豹分支杆菌PCR检测试剂盒Mycobacterium pinniped... napa fort collinsWebCYP11A1 is part of cluster 17 Adrenal gland - Steroid metabolism with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated … meisters phillips wiWeb17 jul. 2024 · In humans, CYP11A1 and CYP11B2 mRNAs have been detected in the colon, suggesting that glucocorticoid synthesis is possible in the human intestine, as observed in mice . Furthermore, glucocorticoids synthesized by intestinal epithelial cells are known to promote epithelial cell proliferation and ameliorate the damage associated with … napa fort mcmurrayWeb3 apr. 2007 · A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid … meister speedkills leather speed bagWebCYP11A1 (D8F4F) Rabbit mAb recognizes endogenous levels of total CYP11A1 protein. Species Reactivity: Human, Mouse, Rat. Source / Purification. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human CYP11A1 protein. meisters on cedar lake new richmond wi